calnexine

OBS: Chaperonne : protéine de forme creuse réalisant un chaperon, ou capuchon, pour couvrir une autre protéine, ce qui évite certaines actions indésirables dans les cellules.

CONT: Calnexin is a 90 kDa [kiloDaltons] integral membrane protein located primarily in the ER [endoplasmic reticulum]. It contains a long N-terminal calcium-binding domain that extends into the lumen of the ER and a short, acidic cytosolic domain. Calnexin associates with several cell surface proteins as they pass through the ER. Since it also forms complexes with other resident ER proteins involved in the Ca2+-dependent retention of proteins, calnexin may act as a chaperone.